Fig. 6.

AAV-13A7-Fc administration ameliorated chronic DSS-induced colitis. Mice (n = 10) received 10¹¹ vg of AAV coding for 13A7-Fc or 14D5-dimHLE and received three cycles of 2.5% DSS in drinking water for 5 days followed by regular water for 15 additional days. Disease activity score (DAI) curves and cumulative and mean DAI scores are shown. Mean ± SEM are shown. Statistical comparison two-way ANOVA (top) or one-way ANOVA (bottom) were performed with *p < 0.05 and **p < 0.01 and ***p < 0.001. A representative experiment out of three is shown