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. 2024 Jan 12;25:16. doi: 10.1186/s13059-023-03149-8

Fig. 8.

Fig. 8

Model for the new regulatory axis RBM5-HOXA9 in AML. RBM5 directly regulates the transcriptional activity of the HOXA9 locus, which maintains proper downstream signaling transduction, including the FLT3-responsive targets in acute myeloid leukemia cells