Table 2. Key Transcripts of Genes and Respective Proteins Associated with Multiple PFAS Exposure Involved in Enriched Cell Processesa.
Gene name | Coded protein | PFDA | PFHxS | PFNA | PFOA | PFOS | PFPA | PFUnDA |
---|---|---|---|---|---|---|---|---|
CD19 | CD19 | −0.037 | −0.059* | −0.068* | −0.052* | −0.071* | 0.060* | −0.019 |
EBF1 | EBF1 | −0.070* | −0.102* | −0.082* | −0.029 | −0.097* | 0.035 | −0.063* |
KDM1A | LSD1 | −0.075* | −0.077* | −0.070* | −0.039 | −0.071* | 0.015 | −0.049* |
POU2F2 | OCT-2 | −0.029* | −0.029* | −0.030* | −0.007 | −0.029* | −0.003 | −0.010 |
SPIB | SPI-B | −0.030 | −0.074* | −0.058* | −0.014 | −0.070* | 0.060* | −0.060* |
TCF3 | E2A | −0.019 | −0.028* | −0.026* | −0.038* | −0.036* | 0.010 | −0.013 |
TCF4 | E2-2 | −0.038 | −0.036 | −0.053* | −0.036 | −0.071* | 0.062* | −0.046* |
Results are expressed as β coefficients produced by linear regression. Statistically significant results (p < 0.05) are marked in bold with *. PFPA = perfluoropentanoate, PFOA = perfluorooctanoate, PFNA = perfluorononanoate, PFDA = perfluorodecanoate, PFUnDA = perfluoroundecanoate, PFHxS = pefluorohexane sulfonate, and PFOS = perfluorooctane sulfonate.