TABLE 1.

Deduced amino acid sequences of V_H chain CDR3 regions and V_H and V_L utilization of the 10 MPhAbs that selectively bind to complement-resistant M. catarrhalis strains^a

Clone	Amino acid at position 94a	CDR3 sequence	VHb	VL
H3	K	G L F S S R F D S	DP47	Vλ3
F3	K	G F R A P K F D S	DP47	Vλ3
F2	R	G W S P R R F D Y	DP47	Vλ3
E9	K	G G T T R R F D S	DP49	Vλ3
A9	R	G K M A R R F D Y	DP49	Vλ3
B12	K	G R M V R R F D S	DP47	Vλ3
D9	K	G R L V R R F D S	DP47	Vλ3
A11	R	G T V V R R F D Y	DP47	Vλ3
D11	R	G K V V R K F D Y	DP49	Vλ3
G1	K	G R L V R P F D S	DP53	Vλ3
CR9A	K	A X X X X X F D S
	R	D               Y
		G

^aFramework position 94 is depicted because it is not fixed in the phage display library. Numbering of amino acids is according to Kabat et al. (20). 

^bV_H nomenclature is according to Tomlinson et al. (32). All sequences are derived from primer CR9A, one of the partially randomized oligonucleotides used to create diversity in CDR3 (8). X, position with randomized amino acids.