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. Author manuscript; available in PMC: 2024 Jan 12.
Published in final edited form as: Antiviral Res. 2019 Jul 2;170:104548. doi: 10.1016/j.antiviral.2019.104548

Figure 4: THEV Co-administration blocks the cellular activity of OSW-1.

Figure 4:

A) Viability of cells using Trypan Blue stain after 24 h of compound treatment or co-administration of OSW-1 (1 nM) with 10,000 nM of ITZ, THEV, or TTP. B) Cytotoxicity of 1 nM OSW-1 at 48 h co-administered with 10,000 nM THEV, TTP, or ITZ in HCT-116 and HEK293 cells. Representative cytotoxicity curves and average GI50 of three independent experiments shown. C) OSBP levels in HCT-116 and HEK293 cells of co-administration of 1 nM of OSW-1 with 10,000 nM of ITZ, THEV or TTP for 24 h. Representative Western blot and average of three independent experiments shown.