Table 3.

Sensitivity, Specificity, and PPV and NPV of BioFire PN Panel Testing on Samples vs Standard Culture as Gold Standard

Bacteria	Sensitivity	Specificity	PPV	NPV
A: Good quality (n = 203)
S pneumoniae	95	84	39	99
S aureus	77	84	24	99
Group B streptococcus	100	91	5	100
Group A streptococcus	100	100	100	100
H influenzae	95	75	29	99
M catarrhalis	100	91	39	100
P aeruginosa	100	98	64	100
Other Gram-negative rod	46	96	63	92
B: Moderate quality (n = 95)
S pneumoniae	—a	87	0	100
S aureus	67	80	10	99
Group B streptococcus	100	90	18	100
Group A streptococcus	100	98	33	100
H influenzae	75	68	12	100
M catarrhalis	—a	91	0	100
P aeruginosa	100	98	50	100
Other Gram-negative rod	74	99	93	94

Data are presented as percentages.

Abbreviations: BioFire PN, BioFire FilmArray Pneumonia Panel; NPV, negative predictive value; PPV, positive predictive value.

^aCannot be determined as the organism never grew in culture.