Comparison 2. Viral influenza vaccine versus control.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Maternal death	1	2116	Risk Ratio (M‐H, Fixed, 95% CI)	4.96 [0.24, 103.24]
2 Infant death (up to 175 days)	1	2049	Risk Ratio (M‐H, Fixed, 95% CI)	0.71 [0.37, 1.37]
3 Perinatal death (stillbirth + death in first week of life)	1	2083	Risk Ratio (M‐H, Fixed, 95% CI)	1.32 [0.73, 2.38]
4 RT‐PCR confirmed influenza in infants	1	2049	Risk Ratio (M‐H, Fixed, 95% CI)	0.51 [0.30, 0.88]
5 RT‐PCR confirmed influenza in women	1	2116	Risk Ratio (M‐H, Fixed, 95% CI)	0.50 [0.29, 0.86]
6 Influenza‐like illness in infants	1	2049	Risk Ratio (M‐H, Fixed, 95% CI)	1.02 [0.94, 1.09]
7 Any respiratory illness in women	1	2116	Risk Ratio (M‐H, Fixed, 95% CI)	0.97 [0.91, 1.04]
8 Any respiratory illness in infants	1	2049	Risk Ratio (M‐H, Fixed, 95% CI)	1.01 [0.95, 1.07]
9 Influenza‐like illness in women	1	2116	Risk Ratio (M‐H, Fixed, 95% CI)	0.96 [0.79, 1.16]
10 Maternal hospitalisation for respiratory infection	1	2116	Risk Ratio (M‐H, Fixed, 95% CI)	8.93 [0.48, 165.70]
11 Infant hospitalisation for respiratory infection	1	2049	Risk Ratio (M‐H, Fixed, 95% CI)	0.85 [0.52, 1.39]
12 Preterm labour	1	2116	Risk Ratio (M‐H, Fixed, 95% CI)	0.92 [0.53, 1.59]
13 Miscarriage (24‐28 weeks)	1	2116	Risk Ratio (M‐H, Fixed, 95% CI)	0.60 [0.14, 2.49]
14 Stillbirth	1	2116	Risk Ratio (M‐H, Fixed, 95% CI)	1.65 [0.73, 3.76]
15 Adverse events: at least one systemic reaction	1	353	Risk Ratio (M‐H, Fixed, 95% CI)	1.06 [0.87, 1.30]
16 Maternal hospitalisation for any infection	1	2116	Risk Ratio (M‐H, Fixed, 95% CI)	2.27 [0.94, 5.49]
17 Neonatal hospitalisation due to sepsis within 28 days of birth	1	2049	Risk Ratio (M‐H, Fixed, 95% CI)	1.60 [0.73, 3.50]