Table 2.

Point estimates and 95% confidence intervals for the covariate effects obtained by Cox model and the latent class model with two classes for the MCI data application.

		Cox model (1 class)		Latent class model (2 classes)
				Class probability		Class-specific survival submodel
Domains	Covariates	$\hat{\mathit{\zeta }}$	95% CI	$\hat{\mathit{\alpha }}$	95% CI	${\hat{\mathit{\zeta }}}_1$	95% CI	${\hat{\mathit{\zeta }}}_1+{\hat{\mathit{\zeta }}}_2$	95% CI
	Intercept	NA	NA	−2.94*	(−5.00,−0.88)	NA	NA	2.03*	(1.26,2.80)
Overall cognition	MMSE	−0.12*	(−0.15,−0.10)	−0.17	(−0.40, 0.07)	−0.14*	(−0.21,−0.07)	−0.09*	(−0.16,−0.03)
Executive function	TB	0.08*	(0.05,0.12)	0.20*	(0.00, 0.40)	−0.01	(−0.14, 0.11)	0.12*	(0.04,0.19)
	DS	−0.11*	(−0.17,−0.05)	−0.77*	(−1.28,−0.26)	0.03	(−0.20, 0.26)	−0.17*	(−0.30,−0.03)
Memory	LMD	−0.41*	(−0.46,−0.35)	0.23	(−0.40, 0.86)	−0.63*	(−0.80,−0.46)	−0.27*	(−0.39,−0.15)
	CF	−0.21*	(−0.27,−0.14)	−0.74	(−1.73, 0.26)	−0.17	(−0.36, 0.02)	−0.13	(−0.29,0.03)
Language	BN	−0.03*	(−0.06,0.00)	0.35*	( 0.15, 0.55)	−0.17*	(−0.26,−0.07)	0.04	(−0.07,0.15)
Attention	TA	−0.04*	(−0.08,0.00)	−0.15	(−0.49, 0.19)	−0.10	(−0.21, 0.01)	0.01	(−0.07,0.10)
	DSF	0.05	(−0.00,0.10)	0.06	(−0.32, 0.44)	0.01	(−0.11, 0.13)	0.07	(−0.10,0.25)
Cerebrovascular	EH	−0.02	(−0.23,0.18)	−1.10	(−2.53, 0.34)	0.39	(−0.16, 0.93)	−0.11	(−0.55,0.33)
Functional abilities	IADLs	0.12*	(0.10,0.14)	0.40*	( 0.03, 0.76)	0.21*	( 0.14, 0.28)	0.03	(−0.05,0.10)
Behavioral assessment	NPI-Q	0.06*	(0.04,0.09)	0.19	(−0.17, 0.55)	0.11*	( 0.03, 0.19)	0.00	(−0.08,0.08)
	GDS	0.07	(−0.07,0.21)	−0.70	(−2.03, 0.62)	0.09	(−0.33, 0.50)	0.12	(−0.30,0.55)
Aging	AGE	0.27*	(0.20,0.33)	0.90*	( 0.39, 1.42)	0.38*	( 0.20, 0.56)	0.01	(−0.20,0.22)

^*Statistically signficant covariate effect based on 95% confidence interval.

Higher scores on TB and TA indicated worse conditions.