Table 1.
Frequently recurrent DEGs from scRNA-seq.
| Functional classification | Gene symble | Number of samples* | Average fold change# |
|---|---|---|---|
| Transcription factor | ATF5 | 6 | 1.81 |
| BHLHE40 | 5 | 1.77 | |
| Cellular interaction | LGALS1 | 9 | 2.93 |
| LGALS3 | 6 | 2.20 | |
| SPINT2 | 6 | 1.99 | |
| CXCL13 | 5 | 4.42 | |
| LAIR2 | 5 | 1.77 | |
| ITM2A | 5 | 1.63 | |
| CLU | 5 | 1.48 | |
| Cell metabolism | GAPDH | 7 | 2.33 |
| TPI1 | 7 | 2.09 | |
| SMS | 5 | 1.79 | |
| signal transduction | S100A6 | 8 | 1.78 |
| S100A11 | 8 | 1.48 | |
| S100A10 | 6 | 1.56 | |
| S100A4 | 5 | 1.68 | |
| ANXA2 | 5 | 1.64 | |
| cytoskeleton | LMNA | 6 | 2.04 |
| TUBA1B | 5 | 1.96 | |
| TAGLN2 | 5 | 1.51 | |
| mitosis | STMN1 | 5 | 1.90 |
| PTTG1 | 5 | 1.84 | |
| cellular transportation | MFSD10 | 5 | 1.59 |
| cancer-testis antigen | PAGE5 | 5 | 1.89 |
| CST7 | 5 | 1.60 | |
| redox reaction | PRDX1 | 5 | 1.92 |
| Protein folding | PPIA | 6 | 1.49 |
| IncRNA | AC006129.4 | 5 | 1.76 |
*the number of samples where this gene differentially upregulated in malignant T cells (fold change>1.48 and p.adj<0.05). #Average fold change was determined between all the malignant T cells and normal T cells from 13 samples.