Fig 4. RORγt mutant mice have a delay in Chlamydia clearance.

(A) IFUs isolated from vaginal swabs at various time points after infection. For wild-type mice n = 10, RORγt mutant (RORγt^M) mice n = 10, and MHC class II-/- mice n = 5. Data is combined from two experiments, MHC class II-/- group was included in one experiment. Graph is displayed as mean ± SEM. For wild-type versus RORγt^M groups, p<0.05 on days 9 and 16–25. For wild-type versus MHC class II-deficient groups, p<0.05 on days 7–11 and 16–39. For RORγt^M versus MHC class II-deficient groups, p<0.05 on days 11, 19, and 25–39 (2-way ANOVA). (B) Data from A expressed as the percent of mice with culture positive vaginal swabs.