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A: standard curve of 4 kDa FITC-dextran (0.025–1.6 μg/ml). B: The permeability of 4 kDa-FITC dextran was increased after Caco-2 monolayer treated with rTsTryp. C: The rTsTryp increasing permeability was evidently suppressed and abrogated by PAR2 antagonist AZ3451. *P < 0.05 compared to PBS/DMSO groups. #P < 0.05 between two groups.
