FIG. 4.

Dose-dependent inhibition of the binding of salivary agglutinin to rPAc by the sialic acid-specific lectins MAM (○) and SSA (•). Salivary agglutinin (25 μg/ml) was allowed to react with rPAc immobilized on a sensor chip in the presence of various amounts of lectin (0 to 100 μg/ml). The binding is expressed as RU determined by BIAcore assay. Values are given as the means ± standard deviations of triplicate assays. Single asterisk, P < 0.01; double asterisk, P < 0.001 (compared with control [no addition of lectin]).