Table 2.
Spearman correlations between baseline eGFR, serum total CO2, and bone health markers
| Measurement | TCO2 | FGF-23 | PTH | Klotho | 25-D | 1,25-D | U Ca/Cr | B-SAP | CTX-1 | P1NP | TRAP5b |
|---|---|---|---|---|---|---|---|---|---|---|---|
| eGFRa | 0.13 | −0.43a | −0.25a | 0.07 | −0.02 | 0.13 | 0.01 | 0.06 | −0.28a | −0.07 | −0.03 |
| TCO2a | −0.04 | 0.03 | 0.07 | 0.07 | 0.12 | 0.20a | −0.13 | −0.02 | −0.02 | 0.08 | |
| FGF-23a | 0.30a | −0.05 | 0.02 | −0.35a | 0.13 | −0.09 | 0.14 | 0.02 | 0.05 | ||
| PTHa | 0.09 | −0.18a | 0.13 | −0.25 | 0.25a | 0.45a | 0.29 | 0.24 | |||
| Klothoa | −0.02a | 0.06 | −0.03 | 0.23a | −0.04 | 0.05 | 0.05 | ||||
| 25-Da | 0.14 | 0.17a | −0.03 | −0.14 | −0.19a | 0.001 | |||||
| 1,25-Da | 0.01a | 0.12a | −0.01 | −0.06 | 0.09 | ||||||
| Ca/Cra | −0.03 | −0.05 | 0.05 | 0.03 | |||||||
| BSAPa | 0.43a | 0.60a | 0.23a | ||||||||
| CTX-1a | 0.64a | 0.23a | |||||||||
| P1NPa | 0.19a |
1,25-D; 1,25-dihydroxyvitamin D; 25-D, 25-hydroxyvitamin D; B-SAP, bone-specific alkaline phosphatase; Ca/Cr, urine calcium/creatinine; CTX-1, C-terminal telopeptide of type I collagen; FGF-23, fibroblast growth factor-23; P1NP, procollagen type I intact N-terminal propeptide; PTH, parathyroid hormone; TCO2, total CO2; TRAP5b, tartrate-resistant acid phosphatase 5b.
P < 0.05.