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. 2023 Sep 26;40(1):125–137. doi: 10.1007/s43188-023-00211-2

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© The Author(s) under exclusive licence to Korean Society of Toxicology 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

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Fig. 5 — Formation rates of a M4 glucuronide (M4-G) and b M4 sulfate (M4-S) following incubation of 10 μM sylvatesmin (M4) with human cDNA-expressed UGT enzymes (1A1, 1A3, 1A4, 1A6, 1A7, 1A8, 1A9, 1A10, 2B4, 2B7, 2B10, 2B15, and 2B17) and SULT enzymes (1A1*1, 1A1*2, 1A2, 1A3, 1B1, 1C2, 1E1, and 2A1), respectively. Data points represent the mean ± standard deviation (n = 3). ND not detected (lower limit of quantification: 0.5 pmol/min/mg protein)