FIG. 7.

Amino acid sequence alignment of seven E. chaffeensis OMP-1 proteins and C. ruminantium MAP-1. Aligned positions of amino acids identical to those in OMP-1F are shown with dots. The sequence of C. ruminantium MAP-1 is from the report of Van Vliet et al. (36). Gaps (indicated by dashes) were introduced for optimal alignment of all proteins. Bars indicate a semivariable region (SV) and three hypervariable regions (HV1, HV2, and HV3). The chemically determined N-terminal amino acid sequence of E. chaffeensis P23, which was identical to the amino acid sequence of OMP-1F, is underlined. The arrowhead shows the putative cleavage site of the signal peptide.