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. 2024 Jan 12;13:15. doi: 10.1038/s41377-023-01352-7

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a Average beamline background, i.e., background with gas from injection turned off, plotted after Poisson sampling. b Average measured background, plotted after Poisson sampling. c Measured single diffraction pattern of a single GroEL particle. All patterns are downsampled to 64 × 64 to make features more visible on this figure. In (a) and (b), Poisson sampling is used to make the patterns comparable with the single pattern shown in (c)