Figure 1.

The flowchart to identify functional A-to-I RNA editing events in cancers

A. The collection and pre-processing of multi-omics data across 33 cancer types. B. Diverse down-stream analyses of A-to-I RNA editing events. C. The potentially functional A-to-I RNA editing events related to tumorigenesis. A-to-I, adenosine-to-inosine; TCGA, The Cancer Genome Atlas; RNA-seq, RNA sequencing; SNP, single-nucleotide polymorphism; miRNA, microRNA; 3′-UTR, 3′-untranslated region; lncRNA, long non-coding RNA; TSG, tumor suppressor gene; GTEx, Genotype-Tissue Expression; WT, wild-type.