Table 2.
Survival and Hospitalization Risks by Estimated Glomerular Filtration Rate at Advanced Heart Failure.
| Estimated Glomerular Filtration Rate | P value | |||||
|---|---|---|---|---|---|---|
| <30 | 30–44 | 45–59 | ≥60 | |||
|
| ||||||
| Mortality | ||||||
| Unadjusted | 1.32 (1.10–1.60) | 1.25 (1.03–1.51) | 1.18 (0.98–1.43) | 1.00 (ref) | 0.022 | |
| Adjusteda | 1.30 (1.07–1.57) | 1.02 (0.84–1.25) | 1.07 (0.88–1.29) | 1.00 (ref) | 0.039 | |
| Cardiovascular Mortality | ||||||
| Unadjusted | 1.27 (1.00–1.61) | 1.42 (1.13–1.79) | 1.21 (0.96–1.54) | 1.00 (ref) | 0.026 | |
| Adjusteda | 1.22 (0.96–1.56) | 1.09 (0.86–1.38) | 1.11 (0.87–1.41) | 1.00 (ref) | 0.45 | |
| All-cause hospitalization | ||||||
| Unadjusted | 1.12 (0.89–1.40 | 0.94 (0.75–1.17) | 0.92 (0.76–1.12) | 1.00 (ref) | 0.28 | |
| Adjusteda | 1.09 (0.90–1.32) | 1.05 (0.88–1.26) | 0.96 (0.81–1.26) | 1.00 (ref) | 0.61 | |
| HF hospitalization | ||||||
| Unadjusted | 0.86 (0.65–1.14) | 0.89 (0.68–1.16) | 0.93 (0.71–1.22) | 1.00 (ref) | 0.75 | |
| Adjusteda | 0.86 (0.66–1.13) | 0.99 (0.77–1.26) | 0.97 (0.76–1.23) | 1.00 (ref) | 0.70 | |
Adjusted for age, sex, ejection fraction, body mass index, systolic blood pressure, diabetes, peripheral vascular disease, hypertension, chronic obstructive pulmonary disease, angiotensin converting enzyme inhibitor/ angiotensin receptor blocker/ angiotensin receptor neprilysin inhibitor, beta blocker, mineralocorticoid receptor antagonist.