Table 1.
Patients’ demographics and tumor characteristics of NMIBC patients who underwent adequate BCG, stratified by age group.
| Overall Population (N=632) | Age≤70 (N=355) | Age>70 (N=277) | |||||
|---|---|---|---|---|---|---|---|
| Characteristic | N | % | N | % | N | % | p-value |
| Gender | 0.3 | ||||||
| Male | 505 | 79.9 | 278 | 78.3 | 227 | 82.0 | |
| Smoker | 0.7 | ||||||
| Never | 203 | 32.2 | 116 | 32.8 | 87 | 31.4 | |
| Current/Past | 428 | 67.8 | 238 | 67.2 | 190 | 68.6 | |
| Grade | 0.13 | ||||||
| High | 574 | 90.8 | 317 | 89.3 | 257 | 92.8 | |
| Stage of entry TURBT | 0.6 | ||||||
| Ta | 306 | 48.4 | 168 | 47.3 | 138 | 49.8 | |
| Tis | 48 | 7.6 | 25 | 7.0 | 23 | 8.3 | |
| T1 | 278 | 44.0 | 162 | 45.6 | 116 | 41.9 | |
| Tumor | 0.11 | ||||||
| Recurrent | 209 | 33.1 | 108 | 30.4 | 101 | 36.5 | |
| Variant Histology | 0.6 | ||||||
| Yes | 27 | 4.3 | 14 | 4.0 | 13 | 4.7 | |
| Tumor Size>3 cm | 0.7 | ||||||
| Yes | 312 | 52.7 | 179 | 53.3 | 133 | 52.0 | |
| LVI | 0.7 | ||||||
| Yes | 7 | 1.1 | 3 | 0.9 | 4 | 1.5 | |
| Concomitant CIS | 0.07 | ||||||
| Yes | 202 | 32.0 | 103 | 29.0 | 99 | 35.7 | |
| Focality | 0.052 | ||||||
| Multiple | 312 | 49.6 | 163 | 46.2 | 149 | 54.0 | |
| Prior BCG | 0.4 | ||||||
| Yes | 51 | 8.1 | 26 | 7.3 | 25 | 9.0 | |
| Peri-operative Intravesical Chemotherapy | 0.5 | ||||||
| Yes | 79 | 12.8 | 47 | 13.5 | 32 | 11.9 | |
| Restaging TUR | 0.013 | ||||||
| Yes | 391 | 62.0 | 235 | 66.2 | 156 | 56.5 | |
TURBT: Transurethral resection of bladder; LVI: Lymphovascular invasion, CIS: carcinoma in situ. BCG: Bacillus Calmette-Guerin