Table 2.
Classification of TnpB systems
| Selected TnpB system | Origin | Length (aa) | TAM | Cleavage activity | Target substrates |
|---|---|---|---|---|---|
| ISDra2 | Deinococcus radiodurans | 408 | TTGAT | cleavage | dsDNA and ssDNA |
| ISAba30 | Acinetobacter baumannii | 406 | TGAC | cleavage | dsDNA and ssDNA |
| ISTfu1 | Thermobifida fusca | 397 | TGAT | cleavage | dsDNA and ssDNA |
| ISDge10 | Deinococcus geothermalis | 391 | TTAT | cleavage | dsDNA and ssDNA |
| ISYmu1 | Youngiibacter multivorans | 382 | TTGAT | cleavage | dsDNA and ssDNA |
| ISAam1 | Anoxybacillus amylolyticus | 369 | TTTAA | cleavage | dsDNA and ssDNA |
Representative members of the vast TnpB family as characterized by their length (amino acids), TAM, cleavage activity, and target substrates.