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. 2023 Nov 11;32(1):32–43. doi: 10.1016/j.ymthe.2023.11.013

Table 3.

Characteristics of Fanzor endonucleases

Fanzor Origin Length (aa) TAM Cleavage activity Target substrates
SpuFz1 Spizellomyces punctatus 638 CATA cleavage dsDNA
GtFz1 Guillardia theta 690 TTAAN cleavage dsDNA
NlovFz2 Naegleria lovaniensis 477 CCG cleavage dsDNA
MmeFz2 Mercenaria mercenaria 478 TAG cleavage dsDNA

The length (amino acid), TAM, cleavage activity, and target substrates of the eukaryotic type Fanzor endonucleases show their homology to other OMEGA systems.