Supplementary Figure S2.

Paired expression and chromatin accessibility time series data reveal the regulatory landscape for rumen and esophagus development. Hierarchical clustering of gene expression (A) and chromatin accessibility (B) of all samples, including biological and technical replicates. PCAof 14,637 genes (C) and 178,651 open chromatin regions (D). The rumen and esophagus show consistent developmental patterns at both gene expression and chromatin accessibility levels. The variation between the rumen and esophagus is less than the variation among developmental stages. PCA, Principal component analysis.