Table 2.

Differences between scRNA-seq and scDNA-seq used in combination and alone.

Feature/ Function	scRNA-seq	scDNA-seq	scRNA-seq + scDNA-seq
Measures gene expression	Yes	No	Yes
Measures genetic variation (CNVs, SNPs, structural variants)	No	Yes	Yes
Can identify different cell types	Yes	No	Yes
Can identify genetic variants	No	Yes	Yes
Can study gene regulation	Yes	No	Yes
Can track cell differentiation and development	Yes	No	Yes
Can identify genetic variants associated with cell types	No	No	Yes