Table 2.
Bayesian estimation of the frequencies of pathologies by age group and type of hemoglobin variant in male patients.
| Age | Hba | P1 (95 % CR) | P2 (95 % CR) | P3 (95 % CR) | P4 (95 % CR) | P5 (95 % CR) | P6 (95 % CR) | P7 (95 % CR) | P8 (95 % CR) |
|---|---|---|---|---|---|---|---|---|---|
| 18–42 | HbC | 6.12 (0.09–17.78) | 12.45 (1.7–27.03) | 0 (0–0.02) | 0 (0–0.01) | 4.06 (0–14.46) | 57.39 (37.53–76.68) | 2.67 (0–11.79) | 0.65 (0–7.32) |
| 18–42 | HbS | 0.68 (0–5.64) | 16.37 (5.79–29.62) | 6.62 (0.36–16.24) | 0.3 (0–4.38) | 4.52 (0.1–13.07) | 22.03 (9.51–36.74) | 22.53 (9.29–37.43) | 5.17 (0.23–14.52) |
| 18–42 | HbF | 0 (0–0.02) | 0 (0–0.03) | 0 (0–0.02) | 0 (0–0.03) | 0 (0–0.04) | 100 (99.97–100) | 0 (0–0.02) | 0 (0–0.02) |
| 43–55 | HbC | 8.43 (0.13–23.84) | 10.76 (0.41–27.51) | 0 (0–0.02) | 0 (0–0.01) | 0.21 (0–6.79) | 54.16 (31.69–76.64) | 3.69 (0–16.18) | 0.85 (0–9.72) |
| 43–55 | HbS | 5.22 (0.41–13.07) | 5.61 (0.49–13.47) | 0.49 (0–4.33) | 2.44 (0.01–8.54) | 3.62 (0.04–10.32) | 29.32 (16.03–43.08) | 25.11 (13.09–38.79) | 4.05 (0.07–11.03) |
| 56–65 | HbC | 1.47 (0–8.51) | 6.66 (0.33–17.74) | 0 (0–0.01) | 0 (0–0.01) | 0.13 (0–4.02) | 52.69 (34.07–70.43) | 17.43 (5.5–33.18) | 4.22 (0.01–13.66) |
| 56–65 | HbS | 3.06 (0.02–10.01) | 11.51 (3.22–22.7) | 0.53 (0–4.94) | 2.7 (0–9.28) | 1.36 (0–6.85) | 16.32 (6.16–28.9) | 14.33 (4.66–25.99) | 4.49 (0.08–12.05) |
| 56–65 | HgA2 | 0 (0–0.02) | 0 (0–0.03) | 0 (0 - <0.001) | 0 (0–0.02) | 0 (0–0.03) | 0 (0–0.02) | 100 (100–100) | 0 (0–0.02) |
| >65 | HbC | 3.18 (0–17.44) | 5.75 (0–21.26) | 0 (0–0.01) | 0 (0–0.01) | 0.27 (0–8.87) | 58.45 (38.66–76.7) | 12.13 (0.24–31.1) | 8.91 (0.03–27.63) |
| >65 | HbS | 1.11 (0–9.27) | 6.17 (0.06–18) | 1.05 (0–9.28) | 0.51 (0–7.38) | 12.39 (1.87–28.33) | 48.17 (30.61–65.22) | 36.43 (19.22–55.07) | 12.95 (1.69–28.36) |
| >65 | HbF | 0 (0–0.27) | 0 (0–0.37) | 0 (0–0.3) | 0 (0–0.56) | 0 (0–0.3) | 53.03 (31.56–74.33) | 0 (0–0.31) | 0 (0–0.23) |
| >65 | HgA2 | 0 (0–0.31) | 0 (0–0.34) | 100 (100–100) | 0 (0–0.21) | 0 (0–0.31) | 0 (0–0.31) | 0 (0 - <0.001) | 0 (0–0.39) |
| Age | Hba | P9 (95 % CR) | P10 (95 % CR) | P11 (95 % CR) | P12 (95 % CR) | P13 (95 % CR) | P14 (95 % CR) | P15 (95 % CR) | P16 (95 % CR) |
|---|---|---|---|---|---|---|---|---|---|
| 18–42 | HbC | 0 (0–0.01) | 0 (0–0.01) | 0.45 (0–6.56) | 6.05 (0.12–17.77) | 0 (0–0.01) | 0 (0–0.01) | 0 (0–0.01) | 0.88 (0–7.94) |
| 18–42 | HbS | 8.16 (1.06–18.77) | 0 (0–0.01) | 3.86 (0.01–12.01) | 0 (0–0.01) | 0 (0–0.01) | 0.04 (0–2.85) | 0.02 (0–2.39) | 0.24 (0–4.09) |
| 18–42 | HbF | 0 (0–0.02) | 0 (0–0.02) | 0 (0–0.02) | 0 (0–0.02) | 0 (0–0.03) | 0 (0–0.02) | 0 (0–0.02) | 0 (0–0.02) |
| 43–55 | HbC | 0 (0–0.01) | 0 (0–0.01) | 0.61 (0–8.75) | 8.3 (0.1–23.29) | 0 (0–0.01) | 0 (0–0.01) | 0 (0–0.02) | 1.17 (0–10.62) |
| 43–55 | HbS | 6.46 (0.88–14.83) | 0 (0–0.01) | 3.07 (0.01–9.33) | 0 (0–0.01) | 0 (0–0.01) | 0.03 (0–2.22) | 2.02 (0–7.61) | 4.77 (0.36–12.23) |
| 56–65 | HbC | 0 (0–0.01) | 0 (0–0.01) | 7.67 (0.47–19.45) | 1.47 (0–8.67) | 0 (0–0.01) | 0 (0–0.01) | 0 (0–0.01) | 0.74 (0–6.69) |
| 56–65 | HbS | 4.44 (0.26–12.22) | 0 (0–0.01) | 3.34 (0.03–10.37) | 0 (0 - <0.001) | 0 (0 - <0.001) | 2.31 (0–8.56) | 0.02 (0–2.27) | 0.21 (0–3.72) |
| 56–65 | HgA2 | 0 (0–0.02) | 0 (0–0.03) | 0 (0–0.02) | 0 (0–0.02) | 0 (0–0.02) | 0 (0–0.02) | 0 (0–0.02) | 0 (0–0.02) |
| >65 | HbC | 0 (0–0.02) | 0 (0–0.01) | 0.83 (0–11.86) | 3.12 (0–17.26) | 0 (0–0.02) | 0 (0–0.01) | 0 (0–0.02) | 17.4 (1.87–39.48) |
| >65 | HbS | 3.34 (0–13.73) | 0 (0–0.01) | 1.53 (0–10.55) | 0 (0–0.01) | 0 (0–0.01) | 0.08 (0–5.02) | 0.04 (0–4.13) | 0.42 (0–6.94) |
| >65 | HbF | 0 (0–0.27) | 0 (0–0.38) | 0 (0–0.45) | 0 (0–0.34) | 0 (0–0.38) | 0 (0–0.33) | 0 (0–0.5) | 0 (0–0.37) |
| >65 | HgA2 | 0 (0–0.25) | 0 (0–0.4) | 0 (0–0.3) | 0 (0–0.28) | 0 (0–0.38) | 0 (0–0.43) | 0 (0–0.25) | 0 (0–0.46) |
Hb a: hemoglobin.