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. 2024 Jan 13;23:29. doi: 10.1186/s12933-023-02105-x

Table 2.

Cox regression and logistic regression analyses for different end points

Events/total Model 1 Model 2 Model 3
Effect size
(95% CI)
P value Effect size
(95% CI)
P value Effect size
(95% CI)
P value
In-hospital mortality
< 0.50 36/286 1.71 (1.17 − 2.48) 0.005 1.87 (1.28 − 2.73) 0.001 1.56 (1.04 − 2.35) 0.033
0.50–0.74 107/1018 1.39 (1.09–1.77) 0.007 1.42 (1.11–1.81) 0.005 1.33 (1.03–1.71) 0.029
0.75–0.99 222/2854 Ref Ref Ref
1.00–1.24 165/1904 1.12 (0.91–1.39) 0.273 1.13 (0.91–1.39) 0.272 1.10 (0.89–1.36) 0.378
1.25–1.49 103/996 1.37 (1.07–1.75) 0.013 1.37 (1.07–1.75) 0.012 1.34 (1.04–1.72) 0.024
1.50–1.74 59/530 1.49 (1.10 − 2.01) 0.011 1.52 (1.12 − 2.06) 0.007 1.41 (1.03–1.94) 0.030
≥ 1.75 100/680 2.04 (1.59 − 2.63) < 0.001 1.87 (1.28 − 2.73) < 0.001 1.93 (1.48 − 2.52) < 0.001
One-year mortality
< 0.50 160/286 2.19 (1.71 − 2.80) < 0.001 2.70 (2.10–3.48) < 0.001 1.69 (1.28 − 2.24) < 0.001
0.50–0.74 483/1018 1.56 (1.35–1.80) < 0.001 1.65 (1.42–1.92) < 0.001 1.37 (1.17–1.61) < 0.001
0.75–0.99 1047/2854 Ref Ref Ref
1.00–1.24 719/1904 1.05 (0.93–1.18) 0.451 1.05 (0.93–1.19) 0.450 1.00 (0.87–1.13) 0.946
1.25–1.49 414/996 1.23 (1.06–1.42) 0.006 1.24 (1.06–1.44) 0.006 1.16 (0.99–1.36) 0.075
1.50–1.74 236/530 1.39 (1.15–1.67) 0.001 1.45 (1.20–1.76) < 0.001 1.24 (1.01–1.52) 0.042
≥ 1.75 346/680 1.79 (1.51 − 2.12) < 0.001 2.00 (1.68 − 2.39) < 0.001 1.64 (1.36–1.97) < 0.001

Model 1: unadjusted model; Model 2: adjusted by age and sex; Model 3: adjusted by age, sex, urine output, hypertension, DM, AF, acute HF, MI, OMI, stroke, non-ischemic cardiomyopathy, CKD, Nt-pro BNP, SCr, BUN, HbA1c, history of insulin use, vasopressors, loop diuretics, MV, and RRT.