Table 3.
Subgroup analysis evaluating the association between SHR and AKI by means of odds ratios
| Variables | Groups (group 1–7) divided by SHR | P for interaction | ||||||
|---|---|---|---|---|---|---|---|---|
| < 0.50 | 0.50–0.74 | 0.75–0.99 | 1.00–1.24 | 1.25–1.49 | 1.50–1.74 | ≥ 1.75 | ||
| Age | 0.054 | |||||||
| ≥ 65 | 2.04 (1.23–3.39) | 1.30 (1.05–1.62) | Ref | 1.09 (0.92–1.28) | 1.02 (0.83–1.25) | 1.16 (0.88–1.51) | 2.24 (1.68–2.97) | |
| < 65 | 1.79 (1.01–3.20) | 0.97 (0.70–1.35) | Ref | 1.28 (0.99–1.66) | 1.52 (1.09–2.11) | 1.83 (1.17–2.86) | 2.49 (1.69–3.66) | |
| Sex | 0.014 | |||||||
| Male | 2.50 (1.48–4.22) | 1.23 (0.96–1.57) | Ref | 1.08 (0.90–1.29) | 1.16 (0.91–1.46) | 1.65 (1.19–2.28) | 2.97 (2.16–4.08) | |
| Female | 1.51 (1.01–2.77) | 1.18 (0.90–1.55) | Ref | 1.22 (0.99–1.51) | 1.11 (0.86–1.43) | 1.07 (0.77–1.48) | 1.75 (1.26–2.43) | |
| DM | < 0.001 | |||||||
| Yes | 1.74 (1.17–2.60) | 1.16 (0.91–1.47) | Ref | 1.02 (0.83–1.25) | 0.92 (0.72–1.16) | 1.23 (0.91–1.65) | 1.81 (1.38–2.40) | |
| No | 3.05 (0.80–11.7) | 1.14 (0.86–1.52) | Ref | 1.23 (1.02–1.49) | 1.42 (1.10–1.82) | 1.37 (0.94–2.01) | 3.49 (2.33–5.23) | |
| Hypertension | 0.152 | |||||||
| Yes | 2.22 (1.32–3.74) | 1.37 (1.10–1.71) | Ref | 1.22 (1.03–1.44) | 1.20 (0.97–1.49) | 1.36 (1.02–1.80) | 2.05 (1.54–2.71) | |
| No | 1.72 (0.98–3.01) | 0.95 (0.70–1.30) | Ref | 1.00 (0.79–1.28) | 1.04 (0.78–1.40) | 1.22 (0.82–1.81) | 2.82 (1.94–4.13) | |
| CKD | 0.002 | |||||||
| Yes | 1.88 (1.11–3.18) | 1.06 (0.80–1.42) | Ref | 0.94 (0.75–1.20) | 1.15 (0.85–1.56) | 1.33 (0.89–1.98) | 1.71 (1.19–2.47) | |
| No | 1.99 (1.12–3.54) | 1.29 (1.02–1.62) | Ref | 1.25 (1.05–1.48) | 1.14 (0.92–1.41) | 1.27 (0.95–1.69) | 2.60 (1.94–3.41) | |
| Acute HF | 0.017 | |||||||
| Yes | 2.11 (1.25–3.58) | 1.37 (1.09–1.74) | Ref | 1.14 (0.96–1.36) | 1.22 (0.98–1.51) | 1.28 (0.96–1.71) | 2.06 (1.55–2.73) | |
| No | 1.82 (1.04–3.17) | 1.02 (0.77–1.36) | Ref | 1.14 (0.92–1.42) | 1.02 (0.76–1.36) | 1.33 (0.91–1.95) | 3.10 (2.11–4.54) | |
| AMI | 0.429 | |||||||
| Yes | 1.47 (0.62–3.49) | 1.00 (0.64–1.57) | Ref | 0.91 (0.66–1.26) | 0.76 (0.53–1.10) | 1.29 (0.81–2.06) | 1.73 (1.13–2.65) | |
| No | 2.07 (1.36–3.16) | 1.25 (1.02–1.52) | Ref | 1.20 (1.03–1.39) | 1.26 (1.04–1.54) | 1.27 (0.97–1.65) | 2.52 (1.92–3.31) | |
| NICM | 0.312 | |||||||
| Yes | 2.41 (0.69–8.47) | 1.26 (0.75–2.13) | Ref | 1.11 (0.73–1.67) | 0.95 (0.58–1.57) | 1.07 (0.54–2.12) | 1.66 (0.88–3.13) | |
| No | 1.92 (1.29–2.85) | 1.18 (0.98–1.43) | Ref | 1.14 (0.98–1.32) | 1.16 (0.96–1.39) | 1.35 (1.06–1.72) | 2.43 (1.91–3.10) | |
The abbreviations are as same in Table 1