Table 3.
Comparison of HMGB1, NLRP3, Capase-1, and cytokine levels in patients with different duration of seizure
| Variables | duration of seizure ≤ 5 min (N = 22)a |
duration of seizure > 5minnutes (N = 8)a |
P Value |
|---|---|---|---|
| HMGB1 (pg/ml) | 411.9 (338.0–626.5) | 357.8 (325.1–656.2) | 0.798 |
| NLRP3 (pg/ml) | 2365 (1964–3187) | 2071 (1625–3128) | 0.440 |
| Capase-1 (pg/ml) | 2551 (1862–3571) | 2498 (1801–3481) | 0.977 |
| IL-1β (pg/ml) | 82.55 (73.92–131.97) | 121.5 (76.4–164.7) | 0.238 |
| IL-6 (pg/ml) | 40.87 (26.90–55.57) | 37.72 (27.53–52.55) | 0.842 |
| TNF-α (pg/ml) | 181.1 (146.6–284.4) | 191.6 (135.9–234.4) | 0.842 |
FS febrile seizure, HMGB1 high mobility group box-1, IL-1β interleukin-1beta, N number, TNF-α tumor necrosis factor α. The P-value is for Mann–Whitney U-test
aMedian (interquartile range)