Table 1.
Comparisons of Clinicopathological Factors of Breast Cancer Between Patients with Only Primary Breast Cancer (BC) and Patients with Both Primary Breast Cancer and Primary Thyroid Cancer (BC-TC)
| Factors | BC (n=97) | BC-TC (n=97) | p value |
|---|---|---|---|
| Age (years) | |||
| < 55 | 56 (57.7%) | 63 (64.9%) | 0.376 |
| ≥ 55 | 41 (42.3%) | 34 (35.1%) | |
| Family history of breast cancer | |||
| Yes | 8 (8.2%) | 11 (11.3%) | 0.630 |
| No | 89 (91.8%) | 86 (88.7%) | |
| Family history of thyroid cancer | |||
| Yes | 3 (3.1%) | 6 (6.2%) | 0.497 |
| No | 94 (96.9%) | 91 (93.8%) | |
| Menstrual state | |||
| Post-menopause | 54 (55.7%) | 47 (48.4%) | 0.589 |
| Pre-menopause | 36 (37.1%) | 41 (42.3%) | |
| Perimenopause | 7 (7.2%) | 9 (9.3%) | |
| Pathological type | |||
| Invasive ductal carcinoma | 71 (73.2%) | 67 (69.1%) | 0.694 |
| Invasive lobular carcinoma | 11 (11.3%) | 13 (13.4%) | |
| Medullary carcinoma | 5 (5.2%) | 3 (3.1%) | |
| Carcinoma in situ | 10 (10.3%) | 14 (14.4%) | |
| Histological grade | |||
| I | 4 (4.1%) | 1 (1.0%) | 0.108 |
| II | 62 (63.9%) | 53 (54.6%) | |
| III | 31 (32.0%) | 43 (44.4%) | |
| Lymph node metastasis | |||
| Positive | 34 (35.1%) | 25 (25.8%) | 0.212 |
| Negative | 63 (64.9%) | 72 (74.2%) | |
| Tumor size (cm) | |||
| ≤ 2 | 49 (50.5%) | 58 (59.8%) | 0.248 |
| > 2 | 48 (49.5%) | 39 (40.2%) | |
| Estrogen receptor | |||
| Positive | 44 (45.4%) | 66 (68.1%) | 0.002 |
| Negative | 53 (54.6%) | 31 (31.9%) | |
| Progesterone receptor | |||
| Positive | 50 (51.5%) | 69 (71.1%) | 0.008 |
| Negative | 47 (48.5%) | 28 (28.9%) | |
| Human epidermal growth factor receptor | |||
| Positive | 36 (37.1%) | 42 (43.3%) | 0.464 |
| Negative | 61 (62.9%) | 55 (56.7%) | |
| Metastasis classification | |||
| M0 | 91 (93.8%) | 89 (91.8%) | 0.783 |
| M1 | 6 (6.2%) | 8 (8.2%) | |
Notes: The data were shown as n (percentage). The comparisons of data between the two groups were done by Fisher’s exact test or Chi-square test.