Table 2.
Comparison of the hyperreflective layer of the inner choroid between eyes with soft drusen and pachydrusen
| Variables | Eyes with soft drusen (n = 35) | Eyes with pachydrusen (n = 28) | P value |
|---|---|---|---|
| Age, years, mean ± SD | 77.5 ± 7.6 | 66.8 ± 8.6 | < 0.001 |
| Sex, n (%) | |||
| Male | 15 (42.9) | 18 (64.3) | 0.091 |
| Female | 20 (57.1) | 10 (35.7) | |
| Eye, n (%) | |||
| Right | 17 (48.6) | 14 (50.0) | 0.910 |
| Left | 18 (51.4) | 14 (50.0) | |
| Central macular thickness (μm), mean ± SD | 229.9 ± 36.5 | 230.3 ± 16.9 | 0.958 |
| Subfoveal choroidal thickness (μm), mean ± SD | 158.7 ± 70.4 | 349.3 ± 111.0 | < 0.001 |
| Drusen within 500 μm of the foveal center, n (%) | |||
| Present | 18 (51.4) | 1 (3.6) | < 0.001 |
| Absent | 17 (48.6) | 27 (96.4) | |
| Hyperreflective layer of the inner choroid, n (%) | |||
| Present | 24 (68.6) | 28 (100) | 0.001 |
| Absent | 11 (31.4) | 0 (0) | |
| OIR of peak reflectance of hyperreflective layer of the inner choroida, mean ± SD | 4.60 ± 0.50 | 4.77 ± 0.59 | 0.266 |
| Peak reflectance of hyperreflective layer of the inner choroida, mean ± SD | 145.3 ± 15.9 | 148.0 ± 14.4 | 0.514 |
| Distance between hyperreflective layer and the RPE-BM complexa | 49.5 ± 13.7 | 47.7 ± 12.2 | 0.588 |
aData and P values were obtained only from the eyes with the hyperreflective layer of the inner choroid
OIR optical intensity ratio, RPE-BM retinal pigment epithelium-Bruch’s membrane, SD standard deviation