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. 2024 Jan 10;17:59–74. doi: 10.2147/IJGM.S442004

Table 3.

The GSEA Analysis of TPM2 in Breast Cancer

ID Setsize NES p.Adjust Core_enrichment
REACTOME_EXTRACELLULAR
_MATRIX_ORGANIZATION
70 6.25 1.175E-09 NCAN/COL11A2/COL9A3/EMILIN3/COL17A1/ACAN/COMP/
EMILIN1/COL7A1/ADAMTS16/KLK2/COL6A2/COL6A1/ELN/
LOXL4/COL1A1/COL8A2/COL16A1/COL9A1/COL11A1/
PCOLCE/ICAM5/HAPLN1/ASPN/MMP14/COL5A3/NCAM1/
COL1A2/COL5A1/MMP11/ADAMTS14/MMP20/MMP2/
MMP10/ITGA11/COL10A1/P4HA3/COL3A1/FBLN2/MFAP2/
EFEMP2/LOXL2/CTSK/HTRA1/MMP13/MFAP4/COL22A1/
GDF5/TPSAB1/BMP1/SPARC/COL18A1/FBN3/COL8A1/
KLK7/COL5A2/LOXL1/BGN/MMP7/CTSG/DCN/BMP2/TLL2/
ADAMTS2/LAMB3
KEGG_FOCAL_ADHESION 24 3.92 1.9948E-09 MYL7/COL11A2/COMP/SHC4/COL6A2/FLNC/MYL9/MYL2/
COL6A1/COL1A1/COL11A1/COL5A3/COL1A2/COL5A1/MYLK/
ITGA11/COL3A1/THBS2/PAK5/COL5A2/LAMB3/PGF/VEGFD
REACTOME_ECM_
PROTEOGLYCANS
21 3.71 2.6276E-08 NCAN/COL9A3/ACAN/COMP/COL6A2/COL6A1/COL1A1/
COL9A1/HAPLN1/ASPN/COL5A3/NCAM1/COL1A2/COL5A1/
COL3A1/SPARC/COL5A2/BGN/DCN
WP_WNT_SIGNALING 13 3.04 4.1206E-06 WIF1/SFRP5/FZD9/FOSL1/NKD2/NOTUM/SFRP2/SFRP4/
SERPINF1/PLAU/WNT6/CAMK2A/WNT5B
WP_PI3KAKT_SIGNALING_
PATHWAY
24 3.14 5.219E-06 COL9A3/COMP/CSF3/COL6A2/NTF4/COL6A1/FGF21/COL1A1/
COL9A1/FGF3/COL1A2/NGFR/ITGA11/THBS2/FGF1/NGF/
LAMB3/PGF/FGF7/VEGFD
KEGG_PATHWAYS_IN_CANCER 17 2.50 0.00040276 KLK3/FGF16/FGF21/FZD9/FGF3/MMP2/FGF1/WNT6/BMP2/
WNT5B/LAMB3/PGF/FGF7/VEGFD
KEGG_REGULATION_OF_
ACTIN_CYTOSKELETON
14 2.46 0.00043929 MYL7/FGF16/MYL9/MYL2/FGF21/FGF3/MYLK/ITGA11/
FGF1/PAK5
REACTOME_CYTOKINE_SIGNALING_
IN_IMMUNE_SYSTEM
24 2.21 0.00268605 CRLF1/CSF3/POMC/LIF/NCAM1/COL1A2/S100B/MMP2/IL34/
NDN/CTSG/EGR1/CAMK2A/TRIM29/JUNB/IFNG/H3C15/RAG2/
IL9/IL21/IL36A/H3C14/H3C11
REACTOME_IMMUNOREGULATORY_
INTERACTIONS_BETWEEN_A_
LYMPHOID_AND_A_NON_
LYMPHOID_CELL
10 1.78 0.03544381 COL17A1/COL1A1/ICAM5/COL1A2/COL3A1/CD300LG/
KIR2DL3/IGHV3-13/KIR2DL4/IGHV2-70
REACTOME_ADAPTIVE_
IMMUNE_SYSTEM
15 1.68 0.03659665 COL17A1/MRC2/COL1A1/ICAM5/COL1A2/UBE2U/
COL3A1/CTSK