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. 2023 Dec 12;27(1):108713. doi: 10.1016/j.isci.2023.108713

Figure 2.

Figure 2

Knockdown TNIK inhibited CRPC cell proliferation

(A) C4-2, 22RV1, and PC3 cells were transfected with TNIK siRNA and lysed 48 h posttransfection. Whole-cell extracts were analyzed by western blotting with the indicated antibodies. Data are shown as mean ± SD. ∗∗∗p < 0.005.

(B) C4-2, 22RV1, and PC3 cells were transfected with siControl or siTNIK, MTT detected cell viability. Data are shown as mean ± SD. ∗∗∗p < 0.005.

(C) C4-2, 22RV1, and PC3 cells were transfected with siControl or siTNIK; transwell detected cell invasion. Scale bars: 100 μm. Significance was determined by a two-tailed t test: Data are shown as mean ± SD. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.005.