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. 2023 Dec 12;27(1):108713. doi: 10.1016/j.isci.2023.108713

Figure 5.

Figure 5

TNIK inhibitor inhibited proliferation and invasion of CRPC cell

(A) C4-2 and PC3 cells were treated with NCB-0846 24 h. Whole-cell extracts were analyzed by western blotting with the indicated antibodies.

(B) C4-2 and PC3 Cells were seeded into 96-well plates and treated with NCB-0846 (10 μm); MTT detected cell viability. Data are shown as mean ± SD. ∗∗p < 0.01, ∗∗∗p < 0.005.

(C) C4-2 and PC3 cells were treated with NCB-0846 (10 μm); transwell detected cell invasion ability. Scale bars: 100 μm. Data are shown as mean ± SD. ∗∗∗p < 0.005.