Fig. 1.

Developmental changes in sleep macro-architecture. A – Sleep macro-architecture metrics stratified by age (3-year nonoverlapping windows from 2.5 to 17.5 years in NCH databank and 2-year nonoverlapping windows from 4.5 to 10 years in CHAT). The error bars represent 95 % confidence intervals for the mean. B. The top row represents duration of sleep stages in minutes from 3 to 16 years (N1 – light blue, N2 – blue, N3 – dark blue, R – red); the second row is as for A, for N2, N3, R proportions with respect to total sleep time. Total sleep time (TST), sleep maintenance efficiency (SME), sleep fragmentation index (SFI), wake time duration after sleep onset (WASO), transition index between NREM and R sleep (TI NR-R). (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)