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. 2024 Jan 14;14:1300. doi: 10.1038/s41598-024-51808-y

Table 1.

Description of 7514 participants included in the present study.

Characteristic All(n = 7514) Tertile of serum uric acid (mg/dl) P value
Tertile 1 (< 4.70) (n = 2498) Tertile 2 (4.70–5.70) (n = 2322) Tertile 3 (> 5.70) (n = 2694)
Age (years) 40.85 ± 14.28 40.26 ± 13.76 41.12 ± 14.77 41.15 ± 14.32 0.0418
Gender, n (%) < 0.0001
 Male 3690 (49.11) 366 (14.66) 1132 (48.77) 2152 (79.88)
 Female 3824 (50.89) 2132 (85.34) 1190 (51.23) 542 (20.12)
Race, n (%) 0.0098
 Mexican American 732 (9.74) 243 (9.73) 242 (10.43) 248 (9.21)
 Other Hispanic 458 (6.09) 177 (7.07) 152 (6.54) 131 (4.85)
 Non-Hispanic White 5009 (66.66) 1650 (66.05) 1496 (64.42) 1858 (68.97)
 Non-Hispanic Black 793 (10.55) 261 (10.46) 261 (11.25) 271 (10.07)
 Other Race 524 (6.97) 167 (6.69) 171 (7.36) 186 (6.90)
Income-poverty ratio, n (%) 0.0081
 Poor 1530 (20.36) 522 (20.89) 523 (22.54) 489 (18.17)
 Nearly poor 606 (8.06) 189 (7.56) 191 (8.22) 226 (8.38)
 Not poor 4929 (65.60) 1643 (65.76) 1464 (63.04) 1818 (67.47)
 Missing 449 (5.98) 145 (5.79) 144 (6.19) 161 (5.98)
Smoke, n (%) < 0.0001
 Yes 2888 (38.44) 879 (35.19) 902 (38.83) 1105 (41.01)
 No 4449 (59.21) 1566 (62.71) 1352 (58.23) 1533 (56.89)
 Missing 177 (2.35) 52 (2.10) 68 (2.94) 57 (2.10)
Alcohol drinking, n (%) < 0.0001
 Yes 5620 (74.80) 1751 (70.10) 1708 (73.57) 2153 (79.93)
 No 1319 (17.56) 521 (20.86) 444 (19.11) 361 (13.40)
 Missing 574 (7.64) 226 (9.04) 170 (7.31) 180 (6.67)
Body Mass Index (kg/m2) 28.18 ± 6.30 25.94 ± 5.44 28.31 ± 6.13 30.08 ± 6.49 < 0.0001
SBP (mmHg) 119.34 ± 14.65 116.06 ± 14.79 119.54 ± 14.41 122.09 ± 14.12 < 0.0001
DBP (mmHg) 71.26 ± 11.26 69.76 ± 10.67 70.75 ± 10.88 73.00 ± 11.82 < 0.0001
Calcium (mg/dL) 9.42 ± 0.34 9.36 ± 0.34 9.43 ± 0.34 9.47 ± 0.34 < 0.0001
Total bilirubin (mg/dL) 0.77 ± 0.30 0.69 ± 0.26 0.75 ± 0.29 0.85 ± 0.33 < 0.0001
Total Protein (g/dL) 7.15 ± 0.44 7.08 ± 0.45 7.15 ± 0.43 7.21 ± 0.43 < 0.0001
Total cholesterol (mg/dL) 196.51 ± 39.49 194.20 ± 39.26 194.05 ± 39.30 200.50 ± 39.50 < 0.0001
Creatinine (mg/dL) 0.85 ± 0.18 0.74 ± 0.15 0.85 ± 0.16 0.95 ± 0.17 < 0.0001
Blood urea nitrogen (mg/dL) 12.30 ± 4.01 11.24 ± 3.62 12.34 ± 4.07 13.20 ± 4.06 < 0.0001
Serum UA (mg/dl) 5.34 ± 1.34 3.91 ± 0.54 5.19 ± 0.32 6.73 ± 0.82 < 0.0001
FeNO (ppb) 13.50 (9.00–19.50) 12.50 (8.50–17.50) 13.50 (9.00–19.50) 14.00 (9.50–20.50) < 0.001
FVC (ml) 4248.72 ± 1054.30 3816.56 ± 818.60 4206.57 ± 1090.78 4664.66 ± 1049.27 < 0.0001
FEV1 (ml) 3436.98 ± 863.91 3113.14 ± 679.10 3399.32 ± 898.03 3753.45 ± 870.25 < 0.0001

Data are presented as n (%), means ± SD or medians (25th percentile-75th percentile). BMI: body mass index; SBP: Systolic blood pressure; DBP: Diastolic blood pressure; FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; UA: uric acid; FeNO: fractional exhaled nitric oxide.