Table 1.
Characteristic | All(n = 7514) | Tertile of serum uric acid (mg/dl) | P value | ||
---|---|---|---|---|---|
Tertile 1 (< 4.70) (n = 2498) | Tertile 2 (4.70–5.70) (n = 2322) | Tertile 3 (> 5.70) (n = 2694) | |||
Age (years) | 40.85 ± 14.28 | 40.26 ± 13.76 | 41.12 ± 14.77 | 41.15 ± 14.32 | 0.0418 |
Gender, n (%) | < 0.0001 | ||||
Male | 3690 (49.11) | 366 (14.66) | 1132 (48.77) | 2152 (79.88) | |
Female | 3824 (50.89) | 2132 (85.34) | 1190 (51.23) | 542 (20.12) | |
Race, n (%) | 0.0098 | ||||
Mexican American | 732 (9.74) | 243 (9.73) | 242 (10.43) | 248 (9.21) | |
Other Hispanic | 458 (6.09) | 177 (7.07) | 152 (6.54) | 131 (4.85) | |
Non-Hispanic White | 5009 (66.66) | 1650 (66.05) | 1496 (64.42) | 1858 (68.97) | |
Non-Hispanic Black | 793 (10.55) | 261 (10.46) | 261 (11.25) | 271 (10.07) | |
Other Race | 524 (6.97) | 167 (6.69) | 171 (7.36) | 186 (6.90) | |
Income-poverty ratio, n (%) | 0.0081 | ||||
Poor | 1530 (20.36) | 522 (20.89) | 523 (22.54) | 489 (18.17) | |
Nearly poor | 606 (8.06) | 189 (7.56) | 191 (8.22) | 226 (8.38) | |
Not poor | 4929 (65.60) | 1643 (65.76) | 1464 (63.04) | 1818 (67.47) | |
Missing | 449 (5.98) | 145 (5.79) | 144 (6.19) | 161 (5.98) | |
Smoke, n (%) | < 0.0001 | ||||
Yes | 2888 (38.44) | 879 (35.19) | 902 (38.83) | 1105 (41.01) | |
No | 4449 (59.21) | 1566 (62.71) | 1352 (58.23) | 1533 (56.89) | |
Missing | 177 (2.35) | 52 (2.10) | 68 (2.94) | 57 (2.10) | |
Alcohol drinking, n (%) | < 0.0001 | ||||
Yes | 5620 (74.80) | 1751 (70.10) | 1708 (73.57) | 2153 (79.93) | |
No | 1319 (17.56) | 521 (20.86) | 444 (19.11) | 361 (13.40) | |
Missing | 574 (7.64) | 226 (9.04) | 170 (7.31) | 180 (6.67) | |
Body Mass Index (kg/m2) | 28.18 ± 6.30 | 25.94 ± 5.44 | 28.31 ± 6.13 | 30.08 ± 6.49 | < 0.0001 |
SBP (mmHg) | 119.34 ± 14.65 | 116.06 ± 14.79 | 119.54 ± 14.41 | 122.09 ± 14.12 | < 0.0001 |
DBP (mmHg) | 71.26 ± 11.26 | 69.76 ± 10.67 | 70.75 ± 10.88 | 73.00 ± 11.82 | < 0.0001 |
Calcium (mg/dL) | 9.42 ± 0.34 | 9.36 ± 0.34 | 9.43 ± 0.34 | 9.47 ± 0.34 | < 0.0001 |
Total bilirubin (mg/dL) | 0.77 ± 0.30 | 0.69 ± 0.26 | 0.75 ± 0.29 | 0.85 ± 0.33 | < 0.0001 |
Total Protein (g/dL) | 7.15 ± 0.44 | 7.08 ± 0.45 | 7.15 ± 0.43 | 7.21 ± 0.43 | < 0.0001 |
Total cholesterol (mg/dL) | 196.51 ± 39.49 | 194.20 ± 39.26 | 194.05 ± 39.30 | 200.50 ± 39.50 | < 0.0001 |
Creatinine (mg/dL) | 0.85 ± 0.18 | 0.74 ± 0.15 | 0.85 ± 0.16 | 0.95 ± 0.17 | < 0.0001 |
Blood urea nitrogen (mg/dL) | 12.30 ± 4.01 | 11.24 ± 3.62 | 12.34 ± 4.07 | 13.20 ± 4.06 | < 0.0001 |
Serum UA (mg/dl) | 5.34 ± 1.34 | 3.91 ± 0.54 | 5.19 ± 0.32 | 6.73 ± 0.82 | < 0.0001 |
FeNO (ppb) | 13.50 (9.00–19.50) | 12.50 (8.50–17.50) | 13.50 (9.00–19.50) | 14.00 (9.50–20.50) | < 0.001 |
FVC (ml) | 4248.72 ± 1054.30 | 3816.56 ± 818.60 | 4206.57 ± 1090.78 | 4664.66 ± 1049.27 | < 0.0001 |
FEV1 (ml) | 3436.98 ± 863.91 | 3113.14 ± 679.10 | 3399.32 ± 898.03 | 3753.45 ± 870.25 | < 0.0001 |
Data are presented as n (%), means ± SD or medians (25th percentile-75th percentile). BMI: body mass index; SBP: Systolic blood pressure; DBP: Diastolic blood pressure; FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; UA: uric acid; FeNO: fractional exhaled nitric oxide.