Fig. 7.

MSNs+miR-146a regulated the in vivo polarization of macrophages and promoted osteogenic marker expression. a IF images and quantitative analysis (n = 5) of the expression of Arg-1 (green) and Runx2 (red) in the defect area of mouse mandible samples after 2 weeks of healing. b IF images and quantitative analysis (n = 8) of the expression of CD86 (red) and Arg-1 (green) in the defect area of the samples after 2 weeks of healing. *P < 0.05, **P < 0.01, ***P < 0.001. One-way ANOVA with Dunnett’s multiple comparisons to the blank group was used