Table 1.
Demographic and outcome data by MODS trajectory in the training dataset.
| Persistent mods | Resolving mods | no mods | p-value | |
|---|---|---|---|---|
| N (%) | 46 (22.7%) | 63 (31.0%) | 92 (46.3%) | |
| Age (Years) | 1.8 (0.5, 4.5) | 2.4 (1.1, 5.2) | 2.9 (1.3, 6.1) | 0.03 |
| Sex, M | 28 (60.8%) | 35 (55.5%) | 50 (53.2%) | 0.69 |
| Race | ||||
| White | 29 (63.0%) | 40 (63.5%) | N/A | 0.83 |
| Black | 11 (23.9%) | 18 (28.5%) | ||
| Other | 6 (13.1%) | 5 (8.0%) | ||
| PRISM-III | 21 (15, 29) | 14 (10, 18) | 1 (0, 10) | 0.01 |
| Day 1 VIS score | 20 (1, 55) | 10 (1, 20) | 0 (0, 0) | 0.07 |
| Source | ||||
| Pulmonary | 9 (20.9%) | 7 (11.2%) | 2 (2.2%) | 0.45 |
| Extrapulmonary | 23 (53.4%) | 28 (44.4%) | 7 (7.6%) | |
| None | 14 (30.4%) | 28 (44.4%) | 83 (90.2%) | |
| Pathogen type | 0.66 | |||
| Gram positive | 19 (59.4%) | 15 (42.8%) | 5 (55.5%) | |
| Gram negative | 10 (31.0%) | 15 (42.8%) | 6 (66.6%) | |
| Viral | 2 (6.6%) | 4 (11.4%) | 0 (0) | |
| Fungal | 1 (3.0%) | 1 (2.8%) | 0 (0) | |
| Outcomes | ||||
| 28-Day mortality | 17 (36.9%) | 1 (1.5%) | 0 (0) | <0.01 |
| PICU free days | 12 (0, 19) | 22 (17, 24) | 23 (19, 25) | <0.01 |
| PICU LOS | 10 (3, 19) | 6 (4, 11) | 5 (3, 8) | 0.02 |
| Hospital LOS | 19 (3, 33) | 10 (8, 21) | 9 (7, 14) | 0.38 |
| Steroid use | 18 (39.2%) | 15 (30.6%) | 4 (4.4%) | 0.38 |
PRISM III: Pediatric Risk of Mortality III score; VIS score: Vasoactive inotropic score; LOS: Length of stay; N/A: Not available.