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. 2024 Jan 8;29:100661. doi: 10.1016/j.lana.2023.100661

Table 2.

U.S. Burden of Disease, 2019.

Cause Prevalence
DALY
YLD
Percent Rank Percent Rank Percent Rank
Other non-communicable diseases 67.77% 1 4.63% 9 6.00% 7
Neurological disorders 46.46% 2 5.28% 8 6.61% 4
Musculoskeletal disorders 40.96% 3 12.50% 3 25.71% 1
Skin and subcutaneous diseases 29.67% 4 1.97% 15 3.89% 11
Unintentional injuries 28.37% 5 3.90% 10 5.21% 8
Digestive diseases 27.46% 6 3.31% 11 1.54% 13
Sense organ diseases 22.13% 7 2.45% 13 5.13% 9
HIV/AIDS and STIs 21.39% 8 0.42% 18 0.33% 20
Diabetes and kidney diseases 20.33% 9 6.08% 7 6.60% 5
Mental disorders 17.03% 10 6.56% 5 13.73% 2
Respiratory infections and TB 16.58% 11 1.49% 17 0.77% 16
Chronic respiratory diseases 15.86% 12 6.31% 6 6.31% 6
Cardiovascular diseases 12.75% 13 15.59% 1 4.57% 10
Neoplasms 8.50% 14 15.05% 2 2.00% 12
Substance use disorders 5.89% 15 6.66% 4 7.10% 3
Nutritional deficiencies 5.59% 16 0.37% 20 0.63% 17
Transport injuries 4.63% 17 2.39% 14 1.40% 14
Self-harm and interpersonal violence 3.70% 18 2.83% 12 0.50% 19
Maternal and neonatal disorders 1.46% 19 1.50% 16 1.20% 15
Enteric infections 0.79% 20 0.40% 19 0.51% 18
Other infectious diseases 0.37% 21 0.22% 21 0.09% 22
NTD and malaria 0.36% 22 0.09% 22 0.18% 21

Percentages for Prevalence, DALYs, and YLDs were calculated based on specific denominators corresponding to each health metric in 2019. The prevalence percentage represents the proportion of cases out of a total prevalence of 311,050,916. Similarly, the DALY percentage is derived from a denominator of 111,074,469, while the YLD percentage is calculated based on a denominator of 53,316,827.

Abbreviations: DALY, disability-adjusted life year; YLD, years of life lost to disability; STI, sexually transmitted disease; TB, tuberculosis; NTD, neglected tropical disease.