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. 2023 Dec 27;67(1):152–164. doi: 10.1021/acs.jmedchem.3c01020

Table 1. CAs of A. castellanii.

CA (gene name) entry ID amino acid count subcellular locationa
α-CA (ACA1_060250) L8GXK3 348 transmembrane
α-CA (ACA1_130470) L8GPJ9 314 transmembrane
α-CA (ACA1_185050) L8H518 279 transmembrane
β-CA (ACA1_164750) L8GR38 288 mitochondrial
β-CA (ACA1_278940) L8H861 280 transmembrane
β-CA (ACA1_365670) L8GLS7 244 cytoplasmic
γ-CA (ACA1_260080) L8GFM8 282 mitochondrial
γ-CA (ACA1_296480) L8HK20 272 mitochondrial
a

The sequences were retrieved from UniProt (entry IDs), and for six CAs the subcellular locations were predicted using DeepTMHMM-tool (https://www.biorxiv.org/content/10.1101/2022.04.08.487609v1.abstract) and TargetP 2.0 (https://services.healthtech.dtu.dk/service.php?TargetP-2.0). Subcellular location for γ-CAs are according to Gawryluk, Gray28 and Gawryluk, Chisholm, Pinto, Gray.29