Table 2. Microsomal t1/2 (min) for (+)-JQ1 and (+)-JQ1-D (0.5 mg/mL Microsomal Protein).
MLM | HLM | |
---|---|---|
(+)-JQ1 | 11.0 | 7.9 |
(+)-JQ1-D | 19.8 | 22.5 |
fold improvement | 1.8 | 2.8 |
MLM | HLM | |
---|---|---|
(+)-JQ1 | 11.0 | 7.9 |
(+)-JQ1-D | 19.8 | 22.5 |
fold improvement | 1.8 | 2.8 |