Table 2.
Variable | β Estimate | Standard Error | OR (95% CI) | p |
FAQ BL | 0.11343 | 0.05109 | 1.1201(1.0212,1.2506) | 0.0264 |
Age | –0.037 | 0.01931 | 0.9637(0.9273, 1.0005) | 0.0553 |
Right Mesio-Temporal 24M% Decline | –4.9433 | 2.6003 | 0.0071(0.0001,1.0319) | 0.0573 |
Left Mesio-Temporal 24M% Decline | –3.9927 | 2.2064 | 0.0184(0.0002,1.2984) | 0.070357 |
Left Mesio-Temporal BL | 0.0001469 | 0.00009555 | 1.0001(0.9999, 1.0003) | 0.124 |
Aβ42 BL | –0.0003298 | 0.0002238 | 0.997(0.9992,1.0001) | 0.14066 |
Left Temporal 24M% Decline | –2.2242 | 1.8093 | 0.1082(0.0028,3.5480) | 0.218936 |
FAQ 24M% Decline | 0.001976 | 0.001686 | 1.0020(0.9986,1.0055) | 0.241 |
Education | –0.05709 | 0.05117 | 0.9445(0.8534,1.0435) | 0.265 |
Posterior Cingulum BL | 0.8017 | 0.7668 | 2.2293(0.4978,10.1865) | 0.296 |
MMSE 24M% Decline | –0.01321 | 0.01361 | 0.9869(0.9595,1.0135) | 0.331794 |
Right Mesio-Temporal BL | 0.00007593 | 0.00008631 | 1.0001(0.9999, 1.0002) | 0.379 |
Right Hippocampus 24M% Decline | 1.3737 | 1.5686 | 3.9500(0.1957,115.2847) | 0.38117 |
Right Hippocampus BL | 0.0001673 | 0.0002238 | 1.0002(0.9997,1.0006) | 0.455 |
MMSE BL | –0.03882 | 0.06323 | 0.9893(0.8807,1.1079) | 0.539 |
APOE | 0.1013 | 0.1783 | 1.1066(0.7813,1.5761) | 0.57 |
Left Hippocampus 24M% Decline | –0.3558 | 1.27 | 0.7006(0.0433,8.2812) | 0.77935 |
Right Temporal 24M% Decline | –0.4655 | 1.9347 | 0.6278(0.0133,27.9509) | 0.809871 |
Left Hippocampus BL | 0.00005174 | 0.0002256 | 1.0001(0.9996,1.0005) | 0.819 |
Right Temporal BL | –0.2322 | 1.0784 | 0.7928(0.0936,6.5742) | 0.83 |
Sex | –0.0495 | 0.2649 | 0.9517(0.5661,1.6015) | 0.852 |
SDMA BL | –0.2359 | 1.1123 | 0.7899(0.0891,7.1498) | 0.832 |
Posterior Cingulum 24M% Decline | 0.1851 | 1.17731 | 1.2033(0.0349,38.9213) | 0.91686 |
Left Temporal BL | –0.09299 | 0.96987 | 0.9112(0.1338,6.1061) | 0.924 |
FAQ, Functional Activities Questionnaire; BL, Baseline Level; 24M, 24 months; MMSE, Mini-Mental State Examination; APOE, apolipoprotein genotype; SDMA, symmetric dimethylarginine.