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. Author manuscript; available in PMC: 2024 Nov 1.
Published in final edited form as: Ann Allergy Asthma Immunol. 2023 Aug 24;131(5):645–654.e2. doi: 10.1016/j.anai.2023.08.017

Table 4.

Coconut Allergy Characteristics. Population–weighted Frequency % (95% CI)

Variable: % (95% CI) of individuals with convincing coconut allergy % (95% CI) of children with convincing coconut allergy % (95% CI) of adults with convincing coconut allergy % (95% CI) of individuals with physician-diagnosed, convincingly IgE-mediated coconut allergy % (95% CI) of children with physician-diagnosed, convincingly IgE-mediated coconut allergy % (95% CI) of adults with physician-diagnosed, convincingly IgE-mediated coconut allergy
Severe coconut Allergic Reaction (i.e. Stringent reaction symptoms occurring within multiple organ systems) 47.5 (40.1–54.9) 43.3 (28.7–59.1) 48.1 (40.1–56.2) 50.2 (40.4–60.0) 38.2 (23.2–55.8) 52.4 (41.3–63.2)
Severe coconut Allergic Reaction (i.e. Wheeze, Fainting/Dizziness and/or hypotension only) 16.1 (10.9–23.2) 21.5 (9.3–42.0) 15.4 (9.9–23.1) 18.3 (11.4–28.0) 12.7 (5.8–25.4) 19.3 (11.5–30.6)
Physician Diagnosed 46.2 (39.1–53.5) 54.9 (39.5–69.5) 44.9 (37.2–53.0) 100 100 100%
Adult–onset coconut Allergy (among adults only) 18.9 (13.4–26.2) n/a 21.7 (15.4–29.8) 21.5 (13.6–32.2) n/a 25.4 (16.3–37.4)
Multiple food allergies 69.8 (62.3–76.4) 73.8 (56.8–85.8) 69.2 (60.9–76.5) 58.8 (48.5–68.4) 68.9 (45.0–85.7) 57.0 (45.5–67.7)
Current epinephrine prescription 40.1 (33.3–47.4) 51.4 (36.3–66.2) 38.5 (31.0–46.5) 55.1 (45.2–64.5) 63.4 (42.3–80.4) 53.6 (42.5–64.2)
Comorbid Peanut Allergy 27.8 (22.3–34.0) 35.8 (24.6–48.8) 26.6 (20.6–33.6) 28.5 (21.1–37.3) 37.2 (23.2–53.8) 26.9 (18.8–37.1)
Comorbid Tree Nut Allergy 20.0 (15.3–25.6) 39.9 (25.6–56.0) 17.0 (12.5–22.8) 20.5 (14.5–28.2) 35.2 (21.1–52.4) 17.8 (11.5–26.6)
Comorbid Almond allergy 15.5 (11.6–20.5) 23.9 (15.1–35.8) 14.3 (10.1–19.8) 17.6 (12.1–25.0) 31.1 (17.9–48.3) 15.2 (9.4–23.6)
Comorbid Cashew allergy 12.2 (9.0–16.3) 22.8 (14.1–34.5) 10.6 (7.3–15.1) 12.7 (8.3–18.9) 30.4 (17.3–47.6) 9.5 (5.3–16.4)
Comorbid Hazelnut allergy 13.8 (10.1–18.7) 30.7 (17.1–48.7) 11.3 (7.9–15.9) 13.9 (9.1–20.6) 24.1 (12.6–41.2) 12.0 (7.1–19.6)
Comorbid Pecan allergy 12.3 (8.9–16.9) 21.8 (13.4–33.4) 11.0 (7.3–16.1) 13.7 (8.9–20.6) 30.1 (17.1–47.3) 10.8 (6.0–18.6)
Comorbid Pistachio allergy 11.5 (8.2–15.9) 20.4 (12.3–31.7) 10.1 (6.7–15.1) 12.6 (8.1–19.1) 24.8 (13.1–41.8) 10.4 (5.9–17.7)
Comorbid Walnut allergy 13.7 (10.1–18.3) 21.7 (13.4–33.2) 12.6 (8.7–17.7) 14.7 (9.8–21.5) 28.7 (16.1–45.8) 12.2 (7.3–19.8)
Comorbid Milk Allergy 18.2 (13.4–24.3) 19.4 (12.3–29.2) 18.0 (12.7–25.0) 13.7 (8.9–20.5) 13.6 (7.7–28.9) 13.4 (8.1–21.2)
Comorbid Shellfish Allergy 16.7 (12.0–22.7) 24.8 (15.8–36.8) 15.5 (10.4–22.4) 13.9 (9.1–20.6) 26.1 (14.2–42.9) 11.7 (6.8–19.3)
Comorbid Egg Allergy 12.8 (9.4–17.2) 23.9 (15.2–35.5) 11.1 (7.6–16.1) 8.4 (5.2–13.4) 17.7 (9.1–31.5) 6.8 (3.5–12.5)
Comorbid Fin Fish Allergy 16.9 (12.0–23.4) 13.0 (7.8–20.9) 17.5 (12.0–24.9) 11.8 (7.1–18.9) 1.4 (5.7–21.7) 11.8 (6.6–20.3)
Comorbid Wheat Allergy 9.0 (6.4–12.5) 17.1 (10.7–26.2) 7.8 (5.2–11.7) 5.0 (2.9–8.5) 14.7 (7.4–27.3) 3.2 (1.4–7.1)
Comorbid Soy Allergy 14.8 (11.0–19.8) 24.2 (15.2–36.2) 13.5 (9.4–19.0) 8.9 (5.3–14.6) 16.6 (8.4–30.3) 7.5 (3.9–14.2)
Coconut Allergy diagnosed by Skin Prick Test Not assessed among those without physician-diagnosis 73.2 (63.8–80.8) 67.0 (45.1–83.4) 74.3 (64.0–82.4)
Coconut Allergy diagnosed by Blood Test Not assessed among those without physician-diagnosis 28.1 (20.4–37.2) 28.1 (16.6–43.3) 28.1 (19.6–38.5)
Coconut Allergy diagnosed by OFC Not assessed among those without physician-diagnosis 20.2 (13.4–29.2) 29.5 (13.5–52.9) 18.5 (11.6–28.2)
Used EAI to treat a coconut-allergic reaction 20.9 (15.8–27.1) 22.3 (13.1–35.4) 20.7 (15.1–27.6) 28.9 (20.4–39.1) 25.2 (13.1–43.0) 29.5 (20.0–41.2)
Used Antihistamines to treat a Coconut-allergic reaction 46.0 (38.8) 53.3 (38.4–67.7) 44.9 (37.0–53.0) 47.5 (38.0–57.2) 42.5 (26.5–60.3) 48.4 (37.7–59.3)
Used Asthma Inlaher to treat a Coconut-allergic reaction 20.1 (14.9–26.6) 37.2 (22.3–55.0) 17.6 (12.4–24.2) 29.5 (21.0–39.8) 34.8 (18.1–56.3) 28.6 (19.3–40.1)
Used Steroids to treat a coconut-allergic reaction 13.3 (9.2–18.9) 22.3 (10.0–42.5) 12.0 (7.9–17.7) 18.6 (12.7–26.4) 20.5 (11.2–34.5) 18.3 (11.7–27.4)
Atopic comorbidities
Has physician-diagnosed Asthma 30.3 (24.1–37.3) 51.5 (36.7–66.1) 27.2 (20.7–34.8) 30.5 (22.2–40.4) 43.1 (26.7–61.2) 28.3 (19.1–39.7)
Has physician-diagnosed eczema 10.9 (7.1–16.4) 7.2 (2.8–17.0) 11.5 (7.3–17.7) 10.9 (6.3–18.2) 9.4 (2.8–27.1) 11.1 (6.1–19.5)
Has physician-diagnosed environmental allergies 31.4 (24.7–39.1) 40.6 (26.2–56.8) 30.1 (22.7–38.6) 28.9 (20.6–39.0) 32.2 (18.8–49.3) 28.3 (19.0–40.0)