Table 1.
Demographic, clinical, and white matter characteristics of the active treatment and the sham group participants at baseline
| Active Treatment (n = 25) | Sham (n = 13) | p | |
| Age, y, mean±SD | 68.36±7.69 | 76.62±9.97 | 0.02 |
| Sex, Male/Female | 7/18 | 8/5 | 0.10 |
| MMSE† score, mean±SD | 20.64±3.15 | 19.77±3.27 | 0.44 |
| ADCS-ADL‡ scale, mean±SD | 64.88±7.95 | 66.23±10.83 | 0.70 |
| Number (%) of APOE¶ ɛ4 positive | 13 (52.00%) | 7 (53.85%) | 1 |
| White matter volume⊤, mean±SD | 449.78±71.57 | 459.07±57.07 | 0.66 |
| T1w/T2w§, mean±SD | 1.34±.23 | 1.29±0.30 | 0.61 |
†MMSE, Mini-Mental State Exam; ‡ADCS-ADL, Alzheimer’s Disease Cooperative Study - Activities of Daily Living; ¶APOE, apolipoprotein E. ⊤Unit: cm3. §Active Treatment (n = 24), Sham (n = 12).