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. Author manuscript; available in PMC: 2024 Jan 15.
Published in final edited form as: Mol Cancer Ther. 2021 Feb 25;20(5):833–845. doi: 10.1158/1535-7163.MCT-20-0495

Figure 4.

Figure 4.

Taxane pre-treatment increases death receptor expression. A. Representative histograms of death receptor expression using flow cytometry. B. Mean fluorescent intensity of DR4 and DR5 compared to isotype control. C. Western blot and relative expression of DR5 in DU145 and PC3 cells treated with 0.25μM CBZ or DTX. D. Representative Western blot and relative expression of DR4 in DU145 and PC3 cells treated with 0.25μM CBZ or DTX. E. Western blot of death receptor expression in siCHOP-knockdown DU145 and PC3 cells treated with DMSO, TRAIL, CBZ or DTX. F. Relative death receptor expression in siCHOP-knockdown DU145 and PC3 cells treated with DMSO, TRAIL, CBZ or DTX. The values represent the mean ± SD (n=6). * p < 0.05, ** p < 0.01, *** p ≤ 0.005, **** p< 0.0001.