Figure 5.

Comparison of T cell subsets expressing VISTA/PD-1/Tim-3/TIGIT in PB between AL amyloidosis and MM. Increased TIGIT⁺ CD3⁺, TIGIT⁺ CD4⁺, TIGIT⁺ CD8⁺ T cells were found in the MM group, while increased PD-1⁺ Treg was found in the AL amyloidosis group. AL = amyloid light chain, MM = multiple myeloma, PB = peripheral blood, PD-1 = programmed cell death-1, Tim-3 = T cell immunoglobulin and mucin-domain-containing-3, TIGIT = T cell immunoreceptor with Ig and ITIM domains, Treg = regulatory T cell, VISTA = V-domain immunoglobulin suppressor of T cell activation.