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. Author manuscript; available in PMC: 2024 Jan 15.
Published in final edited form as: Cell Rep. 2023 May 11;42(5):112508. doi: 10.1016/j.celrep.2023.112508

Figure 1. HPV E5 downregulated anti-virus and type I IFN response pathways.

Figure 1.

The transcriptomes of HPV E5-expressing CAL-27 and DC2.4 cells were analyzed by RNA-seq.

(A) Volcano plot of differentially expressed genes. Genes with p < 0.05 were defined as differentially expressed.

(B) Venn diagram of downregulated genes in CAL-27 and DC2.4 cells.

(C) Downregulated gene sets in CAL-27 and DC2.4 cells were analyzed by GO. The top 20 pathways are shown.

(D) Heatmap of genes assigned to the downregulated and upregulated pathways.

See also Figure S1 and Tables S1, S2, S3, and S4.