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. Author manuscript; available in PMC: 2024 Jan 15.
Published in final edited form as: Cell Rep. 2023 May 11;42(5):112508. doi: 10.1016/j.celrep.2023.112508

Figure 5. HPV E5 inhibited the cGAS-STING and RIG-I/MDA5 pathways.

Figure 5.

(A) Phosphorylation of STAT1 after IFN-α treatment in CAL-27 cells was analyzed by western blotting. The ratio of p-STAT1/total STAT1 is shown.

(B) mRNA expression in CAL-27 cells was analyzed by qPCR. Cells were treated with IFN-α at 10 ng/mL for 6 or 12 h

(C and D) Basal mRNA expression in CAL-27 cells was analyzed by qPCR.

(E) mRNA expression was analyzed after poly(I:C) treatment for 4 h at the indicated concentrations. LMW, low molecular weight; HMW, high molecular weight.

(F) mRNA expression after STING agonist treatment was analyzed. Cells were treated with 10 μg/mL of STING agonist for 4 h. Data are represented as mean ± SEM (n = 3).