Figure 2.

Associations between markers of nervous system injury and markers of severity of the acute COVID-19 illness. Each bar represents the number of SDs by which the levels of nervous system injury marker vary when the marker of severity is present versus absent (for dichotomous variables, i.e. the presence of thrombosis, ICU admission and confusion) or when the marker of severity varies by 1 SD (for non-dichotomous variables, i.e. WHO class, NEWS score and the duration of admission). The error bars indicate 95% CIs. Uncorrected P-values are reported next to each bar, and Bonferroni-corrected P-values meeting statistical significance thresholds are flagged as follows: *<0.05, **<0.01 and ***<0.001. WHO severity refers to the World Health Organization classification of COVID-19 severity (in terms of oxygen requirement). Very severe impairment, severe impairment and moderate impairment with cognitive impairment refer to predefined clusters of post-COVID impairment.² See Supplementary Figs 4 and 5 for the same results based on different statistical models.