Fig. 3.
D. welbionis J115T improves glucose tolerance to a similar extent to metformin. (a) Fasted glycaemia. (b) Plasma glucose profile during a 2 h OGTT. (c) Plasma insulin levels 30 min before and 15 min after glucose administration. (d) Insulin fold increase between +15 and −30. Number of mice per group: 9–10. Data were analysed using one-way ANOVA followed by Tukey’s post hoc test for parts (a), (c) and (d). *p<0.05; **p<0.01; ***p<0.001. Data were analysed using two-way ANOVA followed by Tukey’s post hoc test for part (b). *p<0.05; **p<0.01; ***p<0.001. Blue asterisks are for comparisons between the HFD and CT groups, maroon asterisks or maroon p value are for comparisons between the HFD and HFD+J115 groups, grey asterisks are for comparisons between the HFD and HFD+J115+metformin groups, orange p value is for comparison between the HFD and HFD+metformin groups, orange asterisks are for comparisons between the metformin and CT groups and black asterisks are for comparisons between HFD+J115 and CT groups. Results are presented as mean±SEM for parts (a), (c) and (d)