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. 2023 Oct 17;41(1):15–29. doi: 10.1007/s10815-023-02937-2

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© The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

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Fig. 6 — Difference analysis of key genes. (A) Relationship network diagram of hub genes from PPI network; (B) Venn diagram of key genes (PPI hub genes, ceRNA hub genes, miRNA-mRNA genes); (C) difference analysis box plot of key genes including UNK (C), PDIA5 (D), CFL2 (E), SRSF1 (F), CELF2 (G), and NEURL1B (H). miRNA: microRNA; mRNA: messenger RNA; ceRNA network: competitive endogenous RNA network; PPI: protein-protein interaction; GO: Gene Ontology; KEGG: Kyoto Encyclopedia of Genes and Genomes; NC: negative control; bPOI: biochemical premature ovarian failure. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001