Fig. 3.

Effect of mutation on NPHP4 stability Comparison of wild type NPHP4 protein structure with its mutant forms. A The structure of wild type NPHP4 protein and its mutant having mutation from proline to arginine at position 151. B Molecular visualization of the WT (left) and variant (right) amino acid. The residues colored in red represents the wild type [52] and variant residue (ARG). C The backbone, which is the same for each amino acid, is colored red. The side chain, which is unique for each amino acid, is colored black